abstract：BACKGROUND:The ability of an intracellular pathogen to establish infection depends on the capacity of the organism to survive and replicate inside the host. Mycobacterium fortuitum is a bacteria that contains genes involved in the detoxification of the oxygen reactive species such as those produced by the host during t...

journal_title：BMC microbiology

authors： Núñez MC,Menéndez MC,Rebollo MJ,García MJ

更新日期：2008-06-19 00:00:00

abstract：BACKGROUND:Coxiella burnetii is the causative agent of Q-fever, a widespread zoonosis. Due to its high environmental stability and infectivity it is regarded as a category B biological weapon agent. In domestic animals infection remains either asymptomatic or presents as infertility or abortion. Clinical presentation i...

journal_title：BMC microbiology

authors： Panning M,Kilwinski J,Greiner-Fischer S,Peters M,Kramme S,Frangoulidis D,Meyer H,Henning K,Drosten C

更新日期：2008-05-19 00:00:00

abstract：BACKGROUND:Fibronectin-binding protein A (FnBPA) mediates adhesion of Staphylococcus aureus to fibronectin, fibrinogen and elastin. We previously reported that S. aureus strain P1 encodes an FnBPA protein where the fibrinogen/elastin-binding domain (A domain) is substantially divergent in amino acid sequence from the a...

journal_title：BMC microbiology

authors： Loughman A,Sweeney T,Keane FM,Pietrocola G,Speziale P,Foster TJ

更新日期：2008-05-08 00:00:00

abstract：BACKGROUND:Sinorhizobium meliloti is an agriculturally important model symbiont. There is an ongoing need to update and improve its genome annotation. In this study, we used a high-throughput pyrosequencing approach to sequence the transcriptome of S. meliloti, and search for new bacterial genes missed in the previous ...

journal_title：BMC microbiology

authors： Mao C,Evans C,Jensen RV,Sobral BW

更新日期：2008-05-02 00:00:00

abstract：BACKGROUND:The currently used genotyping system for the avian zoonotic pathogen Chlamydophila (C.) psittaci has evolved from serology and is based on ompA sequence variations. It includes seven avian and two non-avian genotypes. Restriction enzyme cleavage of the amplified ompA gene and, less frequently, ompA sequencin...

journal_title：BMC microbiology

authors： Sachse K,Laroucau K,Hotzel H,Schubert E,Ehricht R,Slickers P

更新日期：2008-04-17 00:00:00

abstract：BACKGROUND:The catabolite control protein CcpA is a transcriptional regulator conserved in many Gram-positives, controlling the efficiency of glucose metabolism. Here we studied the role of Bacillus cereus ATCC 14579 CcpA in regulation of metabolic pathways and expression of enterotoxin genes by comparative transcripto...

journal_title：BMC microbiology

authors： van der Voort M,Kuipers OP,Buist G,de Vos WM,Abee T

更新日期：2008-04-16 00:00:00

abstract：BACKGROUND:Polycyclic aromatic hydrocarbons (PAHs), widespread pollutants in the marine environment, can produce adverse effects in marine organisms and can be transferred to humans through seafood. Our knowledge of PAH-degrading bacterial populations in the marine environment is still very limited, and mainly originat...

journal_title：BMC microbiology

authors： Lozada M,Riva Mercadal JP,Guerrero LD,Di Marzio WD,Ferrero MA,Dionisi HM

更新日期：2008-03-25 00:00:00

abstract：BACKGROUND:Chronic wound pathogenic biofilms are host-pathogen environments that colonize and exist as a cohabitation of many bacterial species. These bacterial populations cooperate to promote their own survival and the chronic nature of the infection. Few studies have performed extensive surveys of the bacterial popu...

journal_title：BMC microbiology

authors： Dowd SE,Sun Y,Secor PR,Rhoads DD,Wolcott BM,James GA,Wolcott RD

更新日期：2008-03-06 00:00:00

abstract：BACKGROUND:We have previously shown that supernatant from Candida albicans (CA) culture contains a Secretory Interleukin (IL)-12 Inhibitory Factor (CA-SIIF), which inhibits IL-12 production by human monocytes. However, the effect of CA-SIIF on secretion of other cytokines by monocytes is unknown, and detailed character...

journal_title：BMC microbiology

authors： Wang M,Mukherjee PK,Chandra J,Lattif AA,McCormick TS,Ghannoum MA

更新日期：2008-02-19 00:00:00

abstract：BACKGROUND:Atherosclerosis is still the leading cause of death in the western world. Besides known risk factors studies demonstrating Chlamydophila pneumoniae (C. pneumoniae) to be implicated in the progression of the disease, little is known about C. pneumoniae infection dynamics. We investigated whether C. pneumoniae...

journal_title：BMC microbiology

authors： Marino J,Stoeckli I,Walch M,Latinovic-Golic S,Sundstroem H,Groscurth P,Ziegler U,Dumrese C

更新日期：2008-02-19 00:00:00

abstract：BACKGROUND:The phenomenon of misdiagnosing tuberculosis (TB) by laboratory cross-contamination when culturing Mycobacterium tuberculosis (MTB) has been widely reported and it has an obvious clinical, therapeutic and social impact. The final confirmation of a cross-contamination event requires the molecular identificati...

journal_title：BMC microbiology

authors： Martín A,Herranz M,Lirola MM,Fernández RF,INDAL-TB group.,Bouza E,García de Viedma D

更新日期：2008-02-14 00:00:00

abstract：BACKGROUND:The heme acquisition machinery in Streptococcus pyogenes is believed to consist of the surface proteins, Shr and Shp, and heme-specific ATP-binding cassette transporter HtsABC. Shp has been shown to rapidly transfer its heme to the lipoprotein component, HtsA, of HtsABC. The function of Shr and the heme sour...

journal_title：BMC microbiology

authors： Zhu H,Liu M,Lei B

更新日期：2008-01-23 00:00:00

abstract：BACKGROUND:Microbial fuel cells (MFCs) are devices that exploit microorganisms to generate electric power from organic matter. Despite the development of efficient MFC reactors, the microbiology of electricity generation remains to be sufficiently understood. RESULTS:A laboratory-scale two-chamber microbial fuel cell ...

journal_title：BMC microbiology

authors： Ishii S,Shimoyama T,Hotta Y,Watanabe K

更新日期：2008-01-10 00:00:00

abstract：BACKGROUND:DING proteins constitute a conserved and broadly distributed set of proteins found in bacteria, fungi, plants and animals (including humans). Characterization of DING proteins from animal and plant tissues indicated ligand-binding ability suggesting a role for DING proteins in cell signaling and biomineraliz...

journal_title：BMC microbiology

authors： Zhang XX,Scott K,Meffin R,Rainey PB

更新日期：2007-12-18 00:00:00

abstract：BACKGROUND:Susceptibility to Bordetella pertussis infection varies widely. These differences can partly be explained by genetic host factors. HcB-28 mice are more resistant to B. pertussis infection than C3H mice, which could partially be ascribed to the B. pertussis susceptibility locus-1 (Bps1) on chromosome 12. The ...

journal_title：BMC microbiology

authors： Banus S,Vandebriel RJ,Pennings JL,Gremmer ER,Wester PW,van Kranen HJ,Breit TM,Demant P,Mooi FR,Hoebee B,Kimman TG

更新日期：2007-10-12 00:00:00

abstract：BACKGROUND:Salmonella enteritidis is suggested to translocate in the small intestine. In vivo it induces gene expression changes in the ileal mucosa and Peyer's patches. Stimulation of Salmonella translocation by dietary prebiotics fermented in colon suggests involvement of the colon as well. However, effects of Salmon...

journal_title：BMC microbiology

authors： Rodenburg W,Keijer J,Kramer E,Roosing S,Vink C,Katan MB,van der Meer R,Bovee-Oudenhoven IM

更新日期：2007-09-12 00:00:00

abstract：BACKGROUND:Suppression subtractive hybridization (SSH) strategy was used with extraintestinal pathogenic Escherichia coli (EXPEC) that cause avian colibacillosis (avian pathogenic E. coli or APEC) and human urinary tract infections (uropathogenic E. coli or UPEC) to determine if they possessed genes that were host and/...

journal_title：BMC microbiology

authors： Kariyawasam S,Scaccianoce JA,Nolan LK

更新日期：2007-08-30 00:00:00

abstract：BACKGROUND:Listeria monocytogenes has been implicated in several food borne outbreaks as well as sporadic cases of disease. Increased understanding of the biology of this organism is important in the prevention of food borne listeriosis. The infectivity of Listeria monocytogenes ScottA, cultivated with and without oxyg...

journal_title：BMC microbiology

authors： Bo Andersen J,Roldgaard BB,Christensen BB,Licht TR

更新日期：2007-06-14 00:00:00

abstract：BACKGROUND:Mycobacterium avium is an environmental mycobacterium that can be divided into the subspecies avium, hominissuis, paratuberculosis and silvaticum. Some M. avium subspecies are opportunistic pathogens for animals and humans. They are ubiquitous in nature and can be isolated from natural sources of water, soil...

journal_title：BMC microbiology

authors： Johansen TB,Olsen I,Jensen MR,Dahle UR,Holstad G,Djønne B

更新日期：2007-03-05 00:00:00

abstract：BACKGROUND:Tetrahymena thermophila is one of the best characterized unicellular eukaryotes and its genome is sequenced in its entirety. However, the AT-richness of the genome and an unusual codon usage cause problems in cloning and expression of the ciliate DNA. To overcome these technical hiatuses we developed a Cre-d...

journal_title：BMC microbiology

authors： Weide T,Bockau U,Rave A,Herrmann L,Hartmann MW

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Neisseria gonorrhoeae is an obligate human pathogen that causes significant worldwide morbidity. N. gonorrhoeae expresses lipooligosaccharide (LOS), a phase variable molecule that plays an important role during pathogenesis of the organism. Alteration in the structure of gonococcal LOS correlates with altere...

journal_title：BMC microbiology

authors： Patrone JB,Stein DC

更新日期：2007-01-26 00:00:00

abstract：BACKGROUND:The influence of the membrane-bound AAA+ protease FtsH on membrane and cytoplasmic proteins of Corynebacterium glutamicum was investigated in this study. For the analysis of the membrane fraction, anion exchange chromatography was combined with SDS-PAGE, while the cytoplasmic protein fraction was studied by ...

journal_title：BMC microbiology

authors： Lüdke A,Krämer R,Burkovski A,Schluesener D,Poetsch A

更新日期：2007-01-25 00:00:00

abstract：BACKGROUND:The role of Aspergillus fumigatus mycotoxins in the colonization of the respiratory tract by conidia has not been studied extensively, even though patients at risk from invasive aspergillosis frequently exhibit respiratory epithelium damage. In a previous study, we found that filtrates of A. fumigatus cultur...

journal_title：BMC microbiology

authors： Khoufache K,Puel O,Loiseau N,Delaforge M,Rivollet D,Coste A,Cordonnier C,Escudier E,Botterel F,Bretagne S

更新日期：2007-01-23 00:00:00

abstract：BACKGROUND:H-NS is a DNA-binding protein with central roles in gene regulation and nucleoid structuring in Escherichia coli. There are over 60 genes that are influenced by H-NS many of which are involved in metabolism. To determine the significance of H-NS-regulated genes in metabolism and stress tolerance, an hns muta...

journal_title：BMC microbiology

authors： Erol I,Jeong KC,Baumler DJ,Vykhodets B,Choi SH,Kaspar CW

更新日期：2006-08-15 00:00:00

abstract：BACKGROUND:Most group A streptococcal (GAS) vaccine strategies have focused on the surface M protein, a major virulence factor of GAS. The amino-terminus of the M protein elicits antibodies, that are both opsonic and protective, but which are type specific. J14, a chimeric peptide that contains 14 amino acids from the ...

journal_title：BMC microbiology

authors： Yoonim N,Olive C,Pruksachatkunakorn C,Pruksakorn S

更新日期：2006-08-09 00:00:00

abstract：BACKGROUND:Changes in aboveground plant species diversity as well as variations of environmental conditions such as exposure of ecosystems to elevated concentrations of atmospheric carbon dioxide may lead to changes in metabolic activity, composition and diversity of belowground microbial communities, both bacterial an...

journal_title：BMC microbiology

authors： Grüter D,Schmid B,Brandl H

更新日期：2006-07-27 00:00:00

abstract：BACKGROUND:Non-typeable Haemophilus influenzae biofilm formation is implicated in a number of chronic infections including otitis media, sinusitis and bronchitis. Biofilm structure includes cells and secreted extracellular matrix that is "slimy" and believed to contribute to the antibiotic resistant properties of biofi...

journal_title：BMC microbiology

authors： Gallaher TK,Wu S,Webster P,Aguilera R

更新日期：2006-07-19 00:00:00

abstract：BACKGROUND:Most of the studies evaluating the secular trends of blood isolates come from tertiary hospitals in urban areas. We sought to study the trends of the antimicrobial resistance of blood isolates in patients from a rural population hospitalized in a tertiary hospital in a small city in Greece. METHODS:We retro...

journal_title：BMC microbiology

authors： Falagas ME,Bakossi A,Pappas VD,Holevas PV,Bouras A,Stamata E

更新日期：2006-05-02 00:00:00

abstract：BACKGROUND:Campylobacter jejuni is the predominant cause of antecedent infection in post-infectious neuropathies such as the Guillain-Barré (GBS) and Miller Fisher syndromes (MFS). GBS and MFS are probably induced by molecular mimicry between human gangliosides and bacterial lipo-oligosaccharides (LOS). This study desc...

journal_title：BMC microbiology

authors： Godschalk PC,Bergman MP,Gorkink RF,Simons G,van den Braak N,Lastovica AJ,Endtz HP,Verbrugh HA,van Belkum A

更新日期：2006-04-04 00:00:00

abstract：BACKGROUND:Enterobacter sakazakii is an emergent pathogen associated with ingestion of infant formula and accurate identification is important in both industrial and clinical settings. Bacterial species can be difficult to accurately characterise from complex biochemical datasets and computer algorithms can potentially...

journal_title：BMC microbiology

authors： Iversen C,Lancashire L,Waddington M,Forsythe S,Ball G

更新日期：2006-03-13 00:00:00

abstract：BACKGROUND:Porphyromonas gingivalis is the foremost oral pathogen of adult periodontitis in humans. However, the mechanisms of bacterial invasion and the resultant destruction of the gingival tissue remain largely undefined. RESULTS:We report host-P. gingivalis interactions in primary human gingival fibroblast (HGF) c...

journal_title：BMC microbiology

authors： Urnowey S,Ansai T,Bitko V,Nakayama K,Takehara T,Barik S

更新日期：2006-03-08 00:00:00

abstract：BACKGROUND:There is an increasing interest to better understand endosymbiont capabilities in insects both from an ecological point of view and for pest control. Blochmannia floridanus provides important nutrients for its host, the ant Camponotus, while the bacterium in return is provided with a niche to proliferate. Bl...

journal_title：BMC microbiology

authors： Gaudermann P,Vogl I,Zientz E,Silva FJ,Moya A,Gross R,Dandekar T

更新日期：2006-01-09 00:00:00

abstract：BACKGROUND:The microbiological diagnosis of bacterial vaginosis is usually made using Nugent's criteria, a useful but rather laborious scoring system based on counting bacterial cell types on Gram stained slides of vaginal smears. Ison and Hay have simplified the score system to three categories and added a fourth cate...

journal_title：BMC microbiology

authors： Verhelst R,Verstraelen H,Claeys G,Verschraegen G,Van Simaey L,De Ganck C,De Backer E,Temmerman M,Vaneechoutte M

更新日期：2005-10-14 00:00:00

abstract：BACKGROUND:Heterologous prime-boost immunization protocols using different gene expression systems have proven to be successful tools in protecting against various diseases in experimental animal models. The main reason for using this approach is to exploit the ability of expression cassettes to prime or boost the immu...

journal_title：BMC microbiology

authors： Aleshin SE,Timofeev AV,Khoretonenko MV,Zakharova LG,Pashvykina GV,Stephenson JR,Shneider AM,Altstein AD

更新日期：2005-08-02 00:00:00

abstract：BACKGROUND:The dspA (hik33) gene, coding for a putative sensory histidine kinase, is conserved in plastids (ycf26) and cyanobacteria. It has been linked with a number of different stress responses in cyanobacteria. RESULTS:We constructed an insertional mutant of dspA (ycf26) in Synechocystis 6803. We found little phen...

journal_title：BMC microbiology

authors： Morrison SS,Mullineaux CW,Ashby MK

更新日期：2005-08-02 00:00:00

abstract：BACKGROUND:Although Aspergillus fumigatus is an important human fungal pathogen there are few expression systems available to study the contribution of specific genes to the growth and virulence of this opportunistic mould. Regulatable promoter systems based upon prokaryotic regulatory elements in the E. coli tetracycl...

journal_title：BMC microbiology

authors： Vogt K,Bhabhra R,Rhodes JC,Askew DS

更新日期：2005-01-13 00:00:00

abstract：BACKGROUND:Salmonella enterica and Campylobacter jejuni are amongst the more prevalent bacterial pathogens that cause foodborne diseases. These microorganisms are common contaminants of poultry and poultry products. This study was aimed to evaluate the antibacterial activity of metallic copper surfaces on these importa...

journal_title：BMC microbiology

authors： Faúndez G,Troncoso M,Navarrete P,Figueroa G

更新日期：2004-04-30 00:00:00

abstract：BACKGROUND:The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic activities, as well as differences in disposal regulations and enforcement increase the contamina...

journal_title：BMC microbiology

authors： Mendoza J,Botsford J,Hernandez J,Montoya A,Saenz R,Valles A,Vazquez A,Alvarez M

更新日期：2004-04-22 00:00:00

abstract：BACKGROUND:It is well known that expression of certain bacterial genes responds rapidly to such stimuli as exposure to toxic chemicals and physical agents. It is generally believed that the proteins encoded in these genes are important for successful survival of the organism under the hostile conditions. Analogously, t...

journal_title：BMC microbiology

authors： Yamaguchi Y,Tomoyasu T,Takaya A,Morioka M,Yamamoto T

更新日期：2003-08-12 00:00:00

abstract：BACKGROUND:Bacillus mycoides Flügge, a Gram-positive, non-motile soil bacterium assigned to Bacillus cereus group, grows on agar as chains of cells linked end to end, forming radial filaments curving clock- or counter-clockwise (SIN or DX morphotypes). The molecular mechanism causing asymmetric curving is not known: ou...

journal_title：BMC microbiology

authors： Di Franco C,Beccari E,Santini T,Pisaneschi G,Tecce G

更新日期：2002-11-13 00:00:00